I work at the interface between mathematics and biological sciences. I use mathematics to answer biological questions, and biological questions as inspiration for new mathematical tools. My primary interest lies in uncovering the mechanisms of pathogen population dynamics within and between hosts, with special focus on host and pathogen diversity.
I develop mathematical and computational frameworks to understand intervention effects in multi-type pathogen communities, and to quantify the conditions for stability of coexistence in microbial ecosystems. More broadly, I am attracted to complex systems and data-driven integrative approaches, linking processes that occur at different biological, temporal and spatial scales.
My work spans a wide range of biological systems including African trypanosomes and antigenic variation processes, Streptococcus pneumoniae bacteria, Wolbachia-Drosophila-DCV interactions, biological invasion, antimicrobial resistance management, and the kinetics of host immunity.